software
CTCeek
CTCeek is an interactive Shiny application for circulating tumor cell identification and single-cell reference mapping.
It supports upload of query single-cell RNA-seq data, projection onto a curated CTC reference, cell-type prediction, UMAP visualization, and export of results.
About CTCeek
CTCeek is designed to help explore circulating tumor cells from single-cell RNA-seq data using a reference-based workflow built around Seurat mapping. The application provides an interactive interface for upload, preprocessing, reference projection, prediction review, visualization, and download of analysis outputs.
Live application
The live Shiny app is available here:
Resources
Use note
CTCeek is intended as a research tool for exploratory single-cell and liquid biopsy analysis. Results should be interpreted together with experimental design, sample quality, marker expression, and downstream validation.
Citation
When using CTCeek, please cite the CTCeek GitHub repository and Zenodo record:
Please also cite the underlying single-cell reference, Seurat mapping workflow, and related publications where appropriate.