Circulating tumor cells share RNA modules with early embryo trophectoderm and with metastatic cancer

Abstract

This Cancer Communications paper reports that circulating tumor cells share RNA modules with early embryo trophectoderm and metastatic cancer. The study analyzes bona fide CTC single-cell RNA profiles and highlights epithelial and mesenchymal CTC states relevant to metastasis, liquid biopsy, and translational oncology.